Pathophysiological Significances of Serotonin in Pulmonary Circulation
نویسندگان
چکیده
منابع مشابه
[Role of nitric oxide in the control of the pulmonary circulation: physiological, pathophysiological, and therapeutic implications].
Nitric oxide (NO) is an endogenous vasoactive compound that contributes to pulmonary vascular homeostasis and is produced by three nitric oxide synthase (NOS) isoforms-neuronal NOS (nNOS); inducible NOS (iNOS); and endothelial NOS (eNOS)-all three of which are present in the lung. Studies using pharmacological inhibitors or knockout mice have shown that eNOS-derived NO plays an important role i...
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This study was undertaken to test whether the emphasized systemic vasomotion during sympathetic activation in hypertension is shared by the pulmonary circulation. To this end, 10 normotensive and 29 primary hypertensive subjects were investigated during adrenergic stimulation by mental arithmetic and cold pressor test. Both stimuli induced a systemic pressor reaction in both groups, which was m...
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1: 16). After the epidemic 89 (77%) had a four-fold titre rise. Of those under 20 years of age 46 out of 50 had posi,tive titres after the infection. Clinical illness occurred in over 50% of infected subjects. Five years later a follow-up study was done using 75-g oral carbohydrate load glucose tolerance test. Serum neutralizing antibody titres and two-hour plasma glucose levels were measured. ...
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Serotonin (5-hydroxytryptamine, 5-HT) is a biogenic amine that is distributed widely in various body tissues and cell types and possesses a diversity of pharmacological effects at both central and peripheral sites. 5-HT is involved in the control of temperature regulation, cardiovascular function, muscle contraction and endocrine regulation. Peripherally, 5-HT appears to play a major role in pl...
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This small book consists of a series of papers dealing with various aspects of hemodynamics in the macro-circulation of the lungs. The papers have little to say about the micro-circulation or the structure of the vessels themselves. Each paper is followed by a spirited discussion which proves to be a salubrious force against bias. The study group includes some of the most able and experienced i...
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ژورنال
عنوان ژورنال: Japanese Circulation Journal
سال: 1967
ISSN: 0047-1828,1347-4839
DOI: 10.1253/jcj.31.853